GHRP-6

What is GHRP-6 and how does it work?

Growth hormone is a natural peptide hormone from your pituitary gland. In young children, it stimulates growth. In adults, it supports muscle mass, fat metabolism, bone health, and heart health. It typically increases during deep sleep in the middle of the night. Also, its levels decline with age, contributing to age-related body fat gain, loss of lean mass, and slowed metabolism.

Growth hormone also stimulates IGF-1, which manages the effects of growth hormones. Both hormones work together on tissue and bone growth. IGF-1 weakly binds to insulin receptors and may enhance insulin action. In adults, IGF-1 also protects the blood vessels and neurons, making it important for cardiovascular, and cognitive and mental health.

GHRP-6 is the third most potent GHRP. It doesn’t cause desensitization and also has less prolactin and cortisol issues than GHRP-2. It also binds to ghrelin receptors and stimulates appetite.

Benefits and uses

  • Increases ghrelin in the stomach, stimulating hunger and appetite

  • Increases lean mass

  • Restores GH levels in obesity

  • Improves stage 2 sleep

  • Improves joint health

Side effects

  • Strongly increases appetite

  • Temporarily increases cortisol

  • Redness and itchiness at injection site

  • Swelling in the hands and legs

  • Prolonged use and oversaturation of receptors may increase anxiety and depression

  • Hot flashes

Stacks well with:

  • Other GHRH and GHRPs

  • BPC-157 for anabolic and tissue healing benefits

Ways to take:

Growth hormone secretagogues are best away from food, either before bed or first thing in the morning. They can be administered subcutaneously, orally, or intranasally.

Return to the full list of peptides offered at Kona Integrative Health