Ipamorelin

What is ipamorelin and how does it work?

Growth hormone is a natural peptide hormone from your pituitary gland. In young children, it stimulates growth. In adults, it supports muscle mass, fat metabolism, bone health, and heart health. It typically increases during deep sleep in the middle of the night. Also, its levels decline with age, contributing to age-related body fat gain, loss of lean mass, and slowed metabolism.

Growth hormone also stimulates IGF-1, which manages the effects of growth hormones. Both hormones work together on tissue and bone growth. IGF-1 weakly binds to insulin receptors and may enhance insulin action. In adults, IGF-1 also protects the blood vessels and neurons, making it important for cardiovascular, and cognitive and mental health.

Ipamorelin is a 5-amino acid peptide that stimulates the pituitary to secrete GH, boost IGF-1, and inhibit somatostatin. Therefore, it supports growth and repair of muscles.

It is the mildest and most popular GHRP because it can increase GH without desensitization or any increase in cortisol and prolactin even at large doses. It also doesn’t increase hunger. Therefore, it’s the most popular GH secretagogue.

Benefits and uses

  • Increases growth hormone and IGF-1

  • Suppresses somatostatin without increasing hunger

  • Increases bone growth

  • Supports muscle growth and repair

  • Supports gut recovery after bowel resection

  • Supports fat loss and body composition in combination with the right training and nutrition

Stacks well with:

  • Other GHRH and GH secretagogues